Skyscanner

Flights from Madrid Airport to Santiago Metropolitan Region

Travellers and cabin class

Flight deals from Madrid Airport to Santiago Metropolitan Region

Looking for cheap tickets from Madrid Airport to Santiago Metropolitan Region, or a last-minute trip? Find the lowest prices on one-way and return tickets right here.

Flying from Madrid Airport to Santiago Metropolitan Region

Arm yourself with these facts on the fly.
Cheapest flight found£563, Santiago
Cheapest month to flyNovember
Average flight time13 hrs, 26 mins
Average flights per week126
Most popular airlineLATAM Airlines

Frequently asked questions

Yes - direct flights currently operate from Madrid Airport to Santiago Arturo Merino Benitez Airport in Santiago Metropolitan Region.
We looked at all of the upcoming return flights from Madrid Airport to Santiago Metropolitan Region we could find over the next 12 months. It looks like £563 is the best price. This is good, compared to the average Santiago Metropolitan Region ticket price of £857.
The cheapest month to fly from Madrid Airport to Santiago Metropolitan Region is currently November.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Madrid Airport to Santiago Metropolitan Region on Wednesday, 5 November 2025.
If you're flying from Madrid, the cheapest city in Santiago Metropolitan Region to fly into is Santiago. The cheapest airport serving Santiago at the moment is Santiago Arturo Merino Benitez.
The average flight time between Madrid Airport and Santiago Metropolitan Region is 13 hours and 26 minutes.

More travel options

Flights to Beijing Capital Airport with Air ChinaAir France flights to Yaounde Nsimalen AirportFlights to Salt Lake City Airport with American AirlinesJet2 to Pisa AirportCheap KLM flights to Tokyo Narita AirportRyanair flights to Olbia AirportBook cheap Ryanair flights to Pula AirportFlights to Thessaloniki Airport with RyanairFlights to Shannon Airport with Ryanair
Scandinavian Airlines flights to Stockholm Arlanda AirportBook cheap Virgin Atlantic flights to Salt Lake City AirportFlights to London with British AirwaysBritish Airways to New YorkCheap British Airways flights to OrlandoCheap easyJet flights to GlasgowFlights to London with easyJetFlights to London with EmiratesEmirates flights to Sydney
Flights to New York with Norse Atlantic AirwaysBook cheap Ryanair flights to MilanCheap Scandinavian Airlines flights to OsloBook cheap Scandinavian Airlines flights to Stockholm
Cheap return flights to DubaiFlights to Istanbul ProvinceReturn flights to BangkokReturn plane tickets to BaliReturn flights to MaharashtraReturn plane tickets to DelhiPlane tickets to SeoulTickets to TokyoCheap return flights to Lisbon District
Cheap tickets to Balearic IslandsCheap flights to AndalusiaCheap return tickets to Canary IslandsTickets to Community of MadridTickets to CataloniaPlane tickets to LombardyReturn tickets to LazioReturn tickets to EnglandReturn flights to North Holland
Cheap return tickets to Île-de-FranceFlights to New YorkReturn plane tickets to Attica
Cheap tickets to MalagaReturn tickets to Amsterdam SchipholFlights to Athens InternationalCheap flights to AntalyaPlane tickets to BarcelonaTickets to BangkokCheap return tickets to MumbaiCheap return tickets to ColomboReturn flights to Bali (Denpasar)
Flights to DublinTickets to EdinburghCheap return tickets to FaroCheap return flights to MadeiraCheap flights to HanoiReturn tickets to IstanbulReturn flights to KrakowCheap return flights to London GatwickFlights to Lisbon
Return plane tickets to LondonReturn flights to MadridCheap return tickets to ManchesterReturn plane tickets to Manila Ninoy AquinoPlane tickets to New YorkFlights to ParisCheap flights to Palma - MajorcaPlane tickets to PalermoTickets to Marrakech Menara
Plane tickets to RomeCheap return flights to SingaporeReturn flights to TokyoTickets to Venice